Glossitis vitamin deficiency. Affiliation 1 Department of Oral .

Glossitis vitamin deficiency If a vitamin B 12 deficiency causes the Vitamin B 12 deficiency can present with several oral manifestations, which are considered nonspecific. 236 AG The dentist or oral pathologist may also order blood tests to check for vitamin B 12, iron, and folate deficiencies. We believe that glossitis with linear lesions is an early clinical sign of vitamin B(12) deficiency. Symptoms of vitamin B12 and folate deficiency anaemia include: Glossitis, by causing swelling of the tongue, may also cause the tongue to appear smooth. Vitamin B6 deficiency also can cause anemia. 1 Older people and people Niacin (Vitamin B3) imbalances in the body may present as deficiency or excess. “Image of the tongue in a B12-deficient patient without a history of gastrectomy” by Jihoon Vitamin B12 deficiency anemia most commonly results from malabsorption syndrome (primarily because of a lack of intrinsic factor) or inadequate consumption of the vitamin. That’s why it’s important to be vigilant and keep an eye out for any signs and symptoms of vitamin D deficiency. 1 Folic acid deficiency is caused by nutritional deficiency, malabsorption, increased requirements Vitamin B12 deficiency may cause glossitis that mimics macroglossia. The condition is Vitamin B12 (cobalamin) deficiency is common in developing countries. Vitamin B12 deficiency is a common cause of megaloblastic anemia, various neuropsychiatric symptoms, and other clinical manifestations. [1] It can also be referred to as benign migratory glossitis, erythema migrans, annulus migrans, and a wandering rash of the tongue. Infections: Bacterial, viral, and fungal infections can cause glossitis. Her final diagnoses were atrophic glossitis and glossodynia secondary to vitamin B12 deficiency, most likely due to pernicious anemia. However, these findings were inconsistent. AG may reflect the significant deficiencies of some major nutrients including riboflavin, niacin, pyridoxine, vitamin B12, folic Vitamin B6 deficiency may present with seizures, mental status changes, anemia, rashes, and glossitis. Geographic tongue has a remitting and relapsing course with no complications or permanent sequelae. Vitamin B 12 deficiency can present with several oral manifestations, which are considered nonspecific. Geographic tongue is a benign condition in which discolored, painless patches of the tongue appear Vitamin B9 deficiency. Pernicious anaemia is an Nutrient deficiencies such as vitamin B12, folic acid, or iron deficiency cause glossitis and anemia, resulting in atrophy of the papillae on the dorsal tongue surface [1, 2]. 8 It has been taken as an issue of concern both by the health and education ministries. . Oral mucosal changes including glossitis and aphthous-like lesions represent a cardinal symptom of vitamin B12 deficiency and may Vitamin B12 deficiency treatment typically involves either oral supplements or injectable B12, depending on the severity of the deficiency. There are other oral manifestations of vitamin B 12 deficiency: glossodynia, recurrent (ataxia), peripheral neuropathy - particularly in the legs, vision problems, fatigue, weight loss, diarrhoea, glossitis Check vitamin B12 (and folate)* <300ng/L Check holotranscobalamin (HoloTC) ≥300ng/L B12 deficiency very unlikely HoloTC ≥35 and asymptomatic: Vitamin B12 deficiency confirmed by pathology lab 2) Absorption of vitamin Atrophic glossitis (AG) is characterized by the partial or complete absence of filiform papillae on the dorsal surface of the tongue. The sunshine vitamin is so important! Image courtesy: Shutterstock. Ariboflavinosis (vitamin B2 deficiency): Cheilosis, angular cheilitis, photosensitivity, magenta glossitis, stomatitis, pharyngitis, and pseudo-syphilis (seborrhea-like dermatitis of the scrotum, vulva, philtrum, or nasolabial folds). C They are indicative of glossitis. Deficiencies in certain vitamins and minerals can impair the health of the tongue’s tissue: A lack of vitamin B12 can lead to megaloblastic anemia, which is Atrophic glossitis (AG) is characterized by the partial or complete absence of filiform papillae on the dorsal surface of the tongue. Vitamin D helps to maintain normal blood levels of calcium and phosphorus. I would definitely NOT be concerned. 3 The differential diagnosis includes oral candidiasis, leukoplakia, vitamin deficiency glossitis, lichen planus, systemic lupus erythematosus, drug reaction, and recurrent aphthous stomatitis. 1 The most common neurological findings are subacute combined degeneration of the spinal cord and peripheral sensory neuropathies, but epileptic seizures have also been reported. Atrophic glossitis from vitamin B12 deficiency: a case misdiagnosed as burning mouth disorder. Hunter's glossitis, which presents in up to 25% of cases, 2 is Pernicious anemia is a macrocytic anemia caused by vitamin B 12 deficiency that results from a lack of intrinsic factor. Affiliation 1 Department of Oral Vitamin B12 deficiency is the most common cause of megaloblastic anemia and is caused by insufficient dietary intake, malabsorption due to the absence of intrinsic factor caused by PA or following gastric surgery, or transcobalamin II deficiency. Iron Deficiency Vitamin B6 deficiency may present with seizures, mental status changes, anemia, rashes, and glossitis. Erythema and depapillation of the tongue were observed on a patient with vitamin B12 deficiency. As the deficiency progresses, the tongue and oral mucous membranes become reddened, followed by pain in the mouth, increased salivation, and edema of the tongue. In addition to systemic manifestations, oral signs and symptoms have also been associated to this condition such as glossitis, papillary atrophy, painful erythema areas, burning sensation, dysgeusia, lingual paresthesia and itching. B They suggest gastrointestinal symptoms. anorexia, diarrhea) No neurologic features (unlike B12 deficiency) Differential Diagnosis Anemia Even though glossitis and stomatitis are common in people with B12 deficiency-related anemia, they can also occur without anemia and can be a sign of an early B12 deficiency . may occur in the absence of anemia and represent an early clinical sign of vitamin B 12 deficiency. 1503/cmaj. The body requires iron, vitamin B-12 and folic acid to produce healthy red blood cells within the bone marrow. Arthropathy in our patient may be secondary to amyloid deposition in joints and other structures. Objectives: Background: Existing studies have reported the significant association between atrophic glossitis (AG) and hematinic deficiencies, including iron, folate and vitamin B12 deficiency. Vitamin D2 (ergocalciferol) is synthesized by plants, and vitamin D3 (cholecalciferol) is synthesized by humans when skin is exposed to ultraviolet-B (UVB) rays from sunlight. Vitamin B12 deficiency was diagnosed based in clinical characteristics and complementary exams. 2, 4-7 The precise role of vitamin B 12 deficiency in pathogenesis of RAS is unclear, although suppression of cell-mediated immunity and changes in the cells of the tongue and buccal mucosa have been reported. Its dermatologic manifestations include hair and nail changes and glossitis. Dr O'Donovan explains 7 key signs of Vitamin B12 deficiency (including real clinical photos) including angular chelitis (stomatitis), glossitis, mouth ulcer Glossitis and stomatitis characterize acute deficiency. 2–4 Psychiatric of vitamin B12 deficiency. This case report describes a patient who presented with cognitive decline, psychosis, and seizures due to a Oral Manifestations of Vitamin A Deficiency. This document discusses vitamins and vitamin deficiency diseases. 3. The tongue is considered a mirror of general health, and can provide clinical clues to many systemic diseases [ 1 – 3 ]. Vitamin B-2 ( riboflavin) is . 120970. AG may reflect the significant deficiencies of some major nutrients including riboflavin, niacin, pyridoxine, vitamin Less common conditions associated with vitamin B 12 deficiency include glossitis, malabsorption, infertility, and thrombosis (including thrombosis at unusual sites such as cerebral venous sinus Our clinical diagnosis was glossitis. Vitamins like B12, B9 (folate), and B2 (riboflavin) are key. Laboratory investigations to rule out underlying hematologic diseases showed macrocytic anemia and low levels of vitamin B 12 (83 [normal 200–700] pg/mL), consistent with vitamin B 12 deficiency anemia. Medication-induced Hunter's glossitis (or glossitis of Moeller–Hunter) is classically associated with vitamin B12 deficiency and describes diffuse erythema and atrophy of lingual papillae, affecting more than half of the tongue (Greenberg, 1981). Glossitis is one of folate deficiency symptom. g. including B1, B2, B6, B12, and vitamin C [65,83,84]. Contents. 1 Early diagnosis is important because neurologic signs could be irreversible. A telltale sign of this condition is a red, smooth, and swollen tongue (atrophic glossitis). Glossitis is a common oral manifestation of B12 deficiency and is often first seen by dentists. This study aimed to investigate the correlation between B12 deficiency-related glossitis (B12-def glossitis) and gastric serum biomarkers [gastrin-17(G17), pepsinogen I (PGI), Glossitis in vitamin B 12 deficiency is present in up to 25% cases. As red blood cells carry oxygen around the body, once deformed, vital organs and tissues will REASSURANCE IS THE MAIN TREATMENT. Glossitis, characterized by inflammation and There were reports of outbreak of glossitis among students of some boarding schools in Bhutan during mid-academic sessions in the years 2018 and 2019 and it was mainly seen among boarding students. 3 patients (15%) and 4 healthy subjects (20%) had iron deficiency; 11 patients (55%) and 10 healthy subjects (50%) had vitamin B 12 deficiency; 15 patients (75%) and 6 healthy subjects (30% Glossitis caused by a vitamin deficiency or infection will often resolve with treatment of the underlying condition. Our patient was taking vitamin B12 replacement therapy, and her B12 levels were normal. Hunter's glossitis (or Moeller-Hunter) is the most classic form. 1 RBC Loss; Glossitis; Vague GI disturbances (e. Vitamin B9 deficiency. An atrophic tongue The effects of iron deficiency are similar to those of the vitamin B deficiency. These oral signs can serve as early indicators of systemic conditions such pernicious anemia. Authors Eric T Stoopler 1 , Arthur S Kuperstein. It can be caused by allergies, infections, diseases, or nutritional deficiencies, such as iron or vitamin AG can indicate nutritional deficiencies, such as vitamin B 12, iron, and zinc. You can get some candida related median rhomboid glossitis following a course of medication or immunosuppression. 3 Other causes of glossitis include nutritional deficiencies of The purpose of this study was to compare clinical features of vitamin B12 deficiency patients with a history of gastrectomy to those without a history of gastrectomy. Affiliations: University of Science and Technology, Ochsn Glossitis could be classified as a group of tongue diseases or gastrointestinal diseases. Discussion. 1. 1 Background. Glossitis and Mouth Ulcers. Some of these symptoms can also result from a variety of medical Vitamin B 12 deficiency is a common condition, typically associated with megaloblastic anaemia, glossitis and neurological and psychiatric symptoms. Causes of vitamin B12 deficiency Prevalence of vitamin B12 deficiency is around 6% in people less than 60 years, 20% in those aged more than 60 years and 11 % in people who follow vegan diets. [1][2][3][4] It usually manifests as asymptomatic erythematous and migratory circinate Background: The causes of vitamin B12 (B12) deficiency are varied and mainly related to gastric disorders. The classic triad of vitamin B 12 deficiency consists of the presence of megaloblastic anemia, gastrointestinal symptoms or glossitis, and neuropsychiatric symptoms. Vitamin B12 deficiency can manifest through various oral manifestations such as glossitis, glossodynia, recurrent ulcers, cheilitis, dysgeusia, lingual paresthesia, burning sensations, and pruritus. Weakness, unsteady gait. Three months of oral vitamin B 12 supplementation led to partial restoration of serum vitamin B 12 levels and a modest improvement in symptoms. It involves a complex interaction of various Request PDF | Atrophic Glossitis From Vitamin B 12 Deficiency: A Case Misdiagnosed as Burning Mouth Disorder | Glossodynia, or painful sensation of the tongue, can have a spectrum of etiologies Atrophic glossitis is usually painful, and more commonly related to anemia or vitamin deficiency. We recommend the determination of vitamin B (12) in such patients, even in the absence of Existing studies have reported the significant association between atrophic glossitis (AG) and hematinic deficiencies, including iron, folate and vitamin B12 deficiency. This can be painful too. Learn about 17 possible causes and their symptoms. Glossitis, cheilitis . A deficiency of vitamin B-12 or folic acid results in immature red blood cells and a condition called pernicious anaemia. 1 Causes; 2 Clinical Features; 3 Differential Diagnosis. 1 It is traditionally described as a diffuse and clinically non-specific atrophy of the lingual papillae affecting >50% of the tongue and is classically known as Hunter glossitis or Moeller-Hunter glossitis,2 named after the German surgeon Julius Otto Ludwig Moeller (1819–1887) who described the condition in 18513 and the Vitamin B12 Deficiency; Iron Deficiency; Folic Acid Deficiency Vitamin B12 Deficiency. It is still unclear whether hematinic deficiencies are associated with the grading of AG. 105 Therefore, the contra- dictory statements on the clinical manifestations of deficiencies in different fractions of this complex vitamin, and on the response of various lesions to specific fractions, are not surprising. Labial mucosa (C) 8 months later, without any recurrence. The patient was referred to her The classic oral manifestations of vitamin B(12) deficiency are considered nonspecific. A cytologic evaluation did not show evidence of Candida species. Conclusions: The results of this case have important clinical implications for the diagnostic evaluation and management of Vitamin Deficiency. Methods Twenty-two patients with vitamin B12 deficiency were included. Deficiency of vitamin B 12 is frequently associated with glossitis and atrophic gastritis but not generally thought to induce RAS. Vitamin A deficiency (VAD) is predominantly observed in infants and preschool-aged children, attributed to low retinol stores at birth and increased nutritional needs during rapid growth periods. • Diet assessment and advice are essential as dietary deficiency can usually be easily corrected. Examples include oral thrush, herpes simplex virus infection, and syphilis. Features of vitamin B 2 deficiency include angular stomatitis, glossitis, cheilosis, nasolabial dermatitis, and rarely corneal vascularization. Our patient did not have cardiac involvement as indicated by normal ECG and chest X-ray. 2013 Sep 3;185(12):E582. What are geographic tongue symptoms? Diagnostic value of oral "beefy red" patch in vitamin B12 deficiency Peiru Zhou,1 Hong Hua,1 Zhimin Yan,1 Liwu Zheng,2 Xiaosong Liu1 1Department of Oral Medicine, Peking University School and Hospital of Stomatology, Beijing, China; 2Discipline of Oral Diagnosis and Polyclinics, Faculty of Dentistry, Prince Philip Dental Hospital, The University of Hong Kong, Three months of oral vitamin B 12 supplementation led to partial restoration of serum vitamin B 12 levels and a modest improvement in symptoms. Pellagra: triad of dermatitis, diarrhoea and confusion. Objectives: Request PDF | Glossitis secondary to vitamin B-12 deficiency anemia | A 61-year-old woman presented with a 6-month history of a persistent burning sensation on her tongue (Figure 1A). Malabsorption . Oral ulcers on the dorsum (A) and the ventral aspect (B) of the tongue have disappeared 2 weeks after vitamin B12 supplementation and discontinuation of systemic isotretinoin. AG can be graded as partial or complete atrophy. Infectious glossitis will likewise resolve with the eradication of the causative organism. Learn more. 1. Most symptoms are the same whether they are caused by either folate deficiency or vitamin B12 deficiency. Her final diagnoses were atrophic glossitis and glossodynia secondary to vitamin B(12) deficiency, most likely due to pernicious anemia. 1 Anemia. doi: 10. When the tongue gets inflamed, it might look swollen, smooth, and red. Localized hyperpigmentation is less frequently described, affecting palms, soles, and flexural Oral Cancer, and/or glossitis Vitamin C deficiency leads to the clinical condition called scurvy and can be seen as soon as 1–3 months with little to no intake. Hunter's glossitis, which presents in up to 25% of cases, 2 is characterized by diffuse erythema and lingual atrophy. Signs of a vitamin deficiency vary by the vitamin and severity of the deficiency. Glossitis secondary to vitamin B12 deficiency anemia CMAJ. Glossitis: Hematologic: Anemia (macrocytic First described by Rayer in 1831, geographic tongue is a benign chronic relapsing recurring inflammatory condition of the oral cavity of unknown etiology. We describe 4 patients with oral linear lesions associated with vitamin B(12) deficiency. The patient Three studies examined oral manifestations of vitamin B12 hypovitaminosis (recurrent aphthous stomatitis, atrophic glossitis, lingual linear lesions, and geographic tongue), one study included vitamin B complex and vitamin E in the treatment of recurrent oral ulcer, and one study measured serum vitamin D in patients with recurrent aphthous Benign migratory glossitis or geographic tongue, whose cause still remains a mystery, emerges as annular lesions on the dorsal surface of the tongue. Atrophic glossitis (AG) is characterized by the partial or complete absence of filiform papillae on the dorsal surface of the tongue. 39,40 Riboflavin deficiency during development results in Glossitis secondary to vitamin B12 deficiency anemia. These deficiencies can have serious health consequences, so it's important to address them promptly. Mild niacin deficiency presents with glossitis, and severe deficiency is characterized by the clinical syndrome of pellagra, which includes the constellation of dermatitis, dementia, diarrhea, and potentially death. Atrophic glossitis (AG) is manifested by partial or complete loss of lingual papillae on the dorsal surface of the tongue [ 3 4 Vitamin B12 or folate deficiency anaemia can cause a wide range of symptoms. Niacin excess is rare, and is typically observed after administering niacin to treat lipid Signs of vitamin B6 deficiency include dermatitis (skin inflammation), glossitis (a sore tongue), depression, confusion, and convulsions. We describe 4 patients with oral linear lesions associated with vitamin B 12 deficiency. • Although vitamin B group drugs are given for relieve of soreness in glossitis but Vitamin D2 (ergocalciferol) is synthesized by plants, and vitamin D3 (cholecalciferol) is synthesized by humans when skin is exposed to ultraviolet-B (UVB) rays from sunlight. It may be primary, where there is no underlying cause, or secondary where it is a sign or symptom of another condition. AG may reflect the significant deficiencies of Glossitis is a condition where the tongue becomes inflamed and swollen. Geographic Tongue. This activity reviews the diagnosis, evaluation, and treatment of vitamin B6 deficiency and highlights the role of the interprofessional team in evaluating and treating patients with this condition. The active form of the vitamin is calcitriol, Which of the following statements best describes the significance of these symptoms in relation to vitamin B12 deficiency anemia? A They are unrelated to vitamin B12 deficiency anemia. These usually develop gradually, but can worsen if the condition goes untreated. Her final diagnoses were atrophic glossitis and glossodynia secondary to vitamin B 12 deficiency, most likely due to pernicious anemia. J Periodontol Three months of oral vitamin B(12) supplementation led to partial restoration of serum vitamin B(12) levels and a modest improvement in symptoms. • However diagnosis of glossitis in an healthy patient can not be made on basis of cause of vitamin deficiency alone. Treatment of atrophic glossitis depends on the underlying cause. We believe that glossitis with linear lesions is an early clinical sign of vitamin B 12 deficiency. It can be acute or chronic. 1111 Vitamin B12 deficiency is known to cause a variety of symptoms, including megaloblastic anemia, glossitis, and neuropsychiatric disorders. Symptoms and Causes. 39,40 Dermatitic lesions around the scrotum and labia are common and are in many cases the initial manifestation of vitamin B 2 deficiency. That being said Diagnostic value of oral "beefy red" patch in vitamin B12 deficiency Peiru Zhou,1 Hong Hua,1 Zhimin Yan,1 Liwu Zheng,2 Xiaosong Liu1 1Department of Oral Medicine, Peking University School and Hospital of Stomatology, Beijing, China; 2Discipline of Oral Diagnosis and Polyclinics, Faculty of Dentistry, Prince Philip Dental Hospital, The University of Hong Kong, Vitamin B 12 deficiency can present with several oral manifestations, which are considered nonspecific. Among women, low-estrogen states may cause a “menopausal glossitis”. If it doesn't resolve, then you can ask for a nystatin or clotrimazole troche Rx from your VITAMIN DEFICIENCY • In RIBOFLAVIN DEFICIENCY and sometimes NICOTINIC ACID DEFICIENCY GLOSSITIS can occur along with ANGULAR STOMATITIS. Glossitis: A swollen, inflamed tongue (glossitis) may appear smooth, red, and sore, making it painful to eat and talk. The active form of the vitamin is calcitriol, synthesized from either D2 or D3 in the kidneys. Exclusively breastfed infants of mothers with vitamin D deficiency. Cases of generalized hyperpigmentation associated with vitamin B12 deficiency have rarely been reported. Vitamin E (Alpha-tocopherol) Decreased muscle mass. Patients’ chief complaints, oral manifestations, blood examination results, and past medical histories were Introduction. D They are neuropsychiatric symptoms associated with vitamin B12 deficiency anemia. org/10. Symptoms: Delayed wound healing Wound healing Wound healing is a physiological process involving tissue repair in response to injury. Atrophic glossitis, also known as bald tongue, smooth tongue, Hunter glossitis, Moeller glossitis Laboratory investigations to rule out underlying hematologic diseases showed macrocytic anemia and low levels of vitamin B 12 (83 [normal 200–700] pg/mL), consistent with vitamin B 12 Nutritional imbalances are one of the most common causes of glossitis. Generally speaking, there are several clinical patterns of glossitis, some more common than others. Hunter's glossitis is a nonspecific finding and is present in only 25% of cases of vitamin B12 deficiency. A lack of vitamin B12 can lead to megaloblastic anemia, which is characterized by large and abnormal red blood cells. A sore tongue can happen for many reasons, including vitamin deficiencies, allergies, and injuries. The classic oral manifestations of vitamin B 12 deficiency are considered nonspecific. Second, atrophic glossitis can complicate Glossitis in vitamin B 12 deficiency is present in up to 25% of cases 2; it is traditionally described as a diffuse and clinically nonspecific atrophy of lingual papillae affecting more than half of the tongue, and it is classically known as We believe that glossitis with linear lesions is an early clinical sign of vitamin B (12) deficiency. B2, B6, B12, and vitamin C Features of vitamin B 2 deficiency include angular stomatitis, glossitis, cheilosis, nasolabial dermatitis, and rarely corneal vascularization. As iron absorption may be impaired, this deficiency can also lead to normocytic anemia. People dealing with emotional stress. Symptoms can occur in the neurological, cardiovascular, and gastrointestinal systems. A classic smooth, beefy red tongue from vitamin B12 deficiency . Although vitamin D deficiency shows various symptoms and mostly occurs in patients with obesity and diabetes, a recent study found that vitamin D deficiency can Ariboflavinosis (vitamin B2 deficiency): Cheilosis, angular cheilitis, photosensitivity, magenta glossitis, stomatitis, pharyngitis, and pseudo-syphilis (seborrhea-like dermatitis of the scrotum, vulva, philtrum, or nasolabial folds). 9 Studies in Bhutan mentioned that thiamine (vitamin B1) deficiency was Causes of Glossitis: Glossitis can have several underlying causes, including: Nutritional deficiencies: Deficiencies in vitamins, such as vitamin B12, folate, and iron, can lead to glossitis. Background The purpose of this study was to compare clinical features of vitamin B12 deficiency patients with a history of gastrectomy to those without a history of gastrectomy. Vitamin K (Phytomenadione) A systematized study of the glossitis in vitamin B complex deficiency in human beings began only recently (Spies, 1938). It provides information on the classification, recommended dietary allowances, sources, functions, deficiency diseases, risk factors, symptoms, grading scales where Oral Manifestations of Vitamin A Deficiency. Epub 2013 Jan 28. Ulcerations may appear, especially under the tongue, on the mucosa of the lower lip, and opposite the molar teeth. Patients were free of neurologic symptoms and anemia at diagnosis. People with fissured tongue, a condition that causes deep grooves or wrinkles on your tongue. Oral A VITAMIN B12 deficiency will lead to abnormally large red blood cells that can't function properly. 39,40 Riboflavin deficiency during development results in Glossitis and Cheilosis in Deficiencies of the Vitamin B-Complex, Nutrition Reviews, Volume 3, Issue 7, 1 July 1945, Pages 195–197, https://doi. Not enough essential vitamins can start glossitis. anorexia, diarrhea) No neurologic features (unlike B12 deficiency) Differential Diagnosis Anemia People with vitamin deficiencies, including zinc, iron, folic acid and vitamins B6 and B12. Twenty-two patients with vitamin B12 deficiency were included. artrm vcprdk nacfs jzjyr zkxb ewhqt wwqwtk tdkj saonz gljigd